Sibutramine, a diet drug withdrawn

Sibutramine is a diet drug that was booming but because of its significant side effects, has generated much controversy in the medical community. Unlike Xenical, this drug is not focused on inhibiting fat absorption but has a anorectic function acting at the level of central nervous system.

Sibutramine is marketed under various names, such as: Reductil, Repentil and Siluvial, And is designed for people with obesity who have not responded adequately to diet to reduce weight.

La sibutramina could be acquired only by prescriptionBecause the physician should assess the patient's health status and to investigate thoroughly on pre-existing heart conditions to determine if this is an excellent candidate to take the medicine and check the dose.

It is worth to note that currently the marketing of this medicine has been suspended in many countries and is being evaluated in other, as has been verified increased heart problems with its intake, altering the risk-benefit of the drug.

The sibutramna comes in two forms, dose of 10 mg to 15 mg, The latter being the maximum that can be ingested per day. It should take in the morning on an empty stomach with water and without being accompanied by other drugs (glucosamine, Postinor, Levothyroxine, etc) because it can impair the absorption of the same.
People with diabetes, heart problems, hypertension, pregnant women, nursing mothers, with hypercholesterolemia, gastric bypass surgery recently, among others, can not take sibutramine.

During treatment with sibutramine, women must take special care not to become pregnant and that the safety of the drug in these cases has not been proven, which is why experts recommend the use of oral contraceptives or barrier methods to good use.
The most common side effects of sibutramine intake are:

• Insomnia
• Dry mouth
• Flaccidity
• Irritable character
• Constipation
• Disturbance of thought
• Fibromyalgia
• Hypertension
• Headache
• Excessive sweating

Uncommon side effects:

• Tachycardia
• Vasodilation
• Palpitations
• Increased appetite
• Vomiting
• Diarrhea
• Rectal disorders
• Dental Disorders
• Dyspepsia
• Gastroenteritis
• Generalized edema and peripheral
• Thirst
• Arthralgia
• Myalgia
• Tenosynovitis
• Arthritis
• Dizziness
• Paresthesia
• Depression
• Emotional lability
• Agitation
• Anxiety
• Nervousness
• Cramps
• Sinusitis
• Bronchitis
• Dyspnoea
• Laryngitis
• Rash
• Herpes
• Hearing impairment
• Alteration of taste
• Otalgia
• Amblyopia
• Dysmenorrhea
• Urinary infection
• Candidiasis
• Metrorrhagia
• Menstrual disorders

Needless to say that sibutramine is not a magic solution to the problem of obesity alone does not produce significant changes in body weight, treatment must be supplemented with a balanced diet and exercise.